Should You Take L-Theanine With Caffeine?
In one trial, L-theanine with caffeine improved some attention and memory measures and alertness compared with placebo.[1]
Based on Haskell et al., Biological Psychology 2008 · Updated October 10, 2026
L-theanine with caffeine improved attention in one trial[1]
In a crossover trial of 250 mg theanine with 150 mg caffeine, the combination improved some attention and memory measures and alertness compared with placebo.
This is one trial; it tested L-theanine and caffeine alone and together, each against placebo.
Source [1]Haskell CF, et al. The effects of L-theanine, caffeine and their combination on cognition and mood. Biological Psychology. 2008. (PubMed)
Log your supplements and meals, and Aurelo flags pairings like this one in your own stack, with the days they happened.
Get started freeRelated
- Does Caffeine Cancel Out Melatonin?Evening caffeine can delay the body’s own melatonin rhythm.
- Does Caffeine Affect Calcium Absorption?Slightly. Caffeine reduces calcium absorption to a small extent; low vitamin D status reduces it more.
- Does Alcohol Deplete B Vitamins?Yes. Chronic heavy drinking drains thiamin, so it is a reason to keep thiamin covered.
Sources
- Haskell CF, et al. The effects of L-theanine, caffeine and their combination on cognition and mood. Biological Psychology. 2008. PubMed
This page is general information from the cited sources, not medical advice. If you take prescription medication, are pregnant, or manage a health condition, check supplement changes with a pharmacist or doctor.
Aurelo