Aurelo
Aurelo Health / Interactions

Do Iodine and Selenium Work Together?

Selenium and iodine both matter for thyroid hormones; selenium deficiency could make iodine deficiency worse, and the adult upper limit for selenium is 400 mcg a day.[1]

Based on NIH Office of Dietary Supplements — Selenium fact sheet · Updated October 10, 2026

Work togetherEvidence: Probable

Selenium and iodine both matter for thyroid hormones[1]

Why

Selenoproteins take part in thyroid hormone metabolism, and selenium deficiency may make the effects of iodine deficiency worse.

What the source says

Selenium deficiency could make iodine deficiency worse. The adult upper limit for selenium is 400 mcg a day, from food and supplements.

Source [1]Selenium: Fact Sheet for Health Professionals. NIH Office of Dietary Supplements. (ods.od.nih.gov)

Log your supplements and meals, and Aurelo flags pairings like this one in your own stack, with the days they happened.

Get started free

Related

Sources

  1. Selenium: Fact Sheet for Health Professionals. NIH Office of Dietary Supplements. ods.od.nih.gov

This page is general information from the cited sources, not medical advice. If you take prescription medication, are pregnant, or manage a health condition, check supplement changes with a pharmacist or doctor.