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Can You Take Magnesium and Zinc Together?

One study found very high zinc supplement doses, 142 mg a day, can interfere with magnesium absorption and magnesium balance.[1]

Based on NIH Office of Dietary Supplements — Magnesium fact sheet · Updated October 10, 2026

AbsorptionEvidence: Probable

Very high zinc doses reduce magnesium absorption[1]

Why

One study found that very high supplemental zinc, 142 mg a day, interfered with magnesium absorption and upset magnesium balance.

What the source says

The concern is very high-dose zinc supplements.

Source [1]Magnesium: Fact Sheet for Health Professionals. NIH Office of Dietary Supplements. (ods.od.nih.gov)

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Related

Sources

  1. Magnesium: Fact Sheet for Health Professionals. NIH Office of Dietary Supplements. ods.od.nih.gov

This page is general information from the cited sources, not medical advice. If you take prescription medication, are pregnant, or manage a health condition, check supplement changes with a pharmacist or doctor.